For my mini-rex Peter's nails, I trim them once every 1-2 weeks. He probably doesn't need it that often, but I like to do it and it's one of the few things I can do with him.
I've never even worried about hairballs, but he gets hay so I suppose I just will keep not worrying.
As for behavior, well Peter is the most disgusting rabbit you'll ever meet. He farts, grunts, and lunges at me for his food (at which I sacrifice a carrot and he attacks that instead of my fingers!). He doesn't think he should go find a litter-box when he's out of the cage (even when it's only 3 feet away), and he marks. So he's getting neutered soon. Then he'll probably be a better bunny. Even so, I luv my bunny and wouldn't trade him for anything! So yeah, I'm a big advocate of spaying and neutering rabbits, for behavior and health benefits.
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