Mary, I've been reading this thread but I haven't had the time to post anything lately. I'm so happy to hear that the vitamin B12 seems to be helping Puddy.

As you know my Starr has colitis and IBD and he's received many vitamin B12 shots as well as acupuncture treatments with vitamin B12. It's really helped him and has given him his energy level back. I hope that it'll do the same for Puddy. She continues to remain in my thoughts and prayers. Please take care. (((HUGS)))

As far as how quickly the vitamin B12 works, I noticed it almost immediately in Starr. He was running and playing the very next day and seemed to have endless energy.