Would a talk with his doctor or a kindly nurse in the office who could maybe explain in some detail why he needs to take the meds help?? Maybe they could explain how the body works and what the benefits of the meds are. Once I explained to my step daughter the importance of her "puffer" and that she could possibly die (a man I worked with died from his asthma) without it she takes it with her everywhere now. She turns 12 in a couple of weeks.