First, I seriously doubt that your cat is spiteful. Your cat is a cat...an animal that cannot reason like a human.

Understanding her behavior may change your perspective on her actions. I feel badly for your misunderstood kitty.

I don't understand what you mean by her getting on your nerves...Cats play. Cats are curious. Cat like to EAT fish. It sounds like you need to catproof your home. Its just like having a child, they get into things too, not because they are being bratty, but because they are curious and oftentimes bored.

Move the fishbowl to a room your cat doesn't have access to. Buy or make her toys she can play with on her own. Catnip is great for entertaining most cats for a while.

Get a cat babysitting video, a few of my cats really enjoy them. Get a bird feeder outside so she has something to entertain her.

There are a ton of things you can do to entertain your cat. Others have said that getting another cat will keep Meka busy, but I wonder what will happen to them when they knock something else over while playing.