Thanks to all of you. We took Wispurr Ann (aka the Princess) to the vet & it wasn't medical, it was behavioral. So we've used an enzyme cleaner (Rug Doctor brand) and are now using a strong sounding water spray bottle, which seems to be working. I also added another litter box, closer to the livingrm, which of course they ALL (4) like! But that's ok! I asked the vet about Feliway & he said he's used it & it is good - the only possible problem is that if a cat wants to mark it's territory - it will definitely stay away from the spot treated by Feliway, but then go looking for another place to mark.Anyway, we're doing much better & thanks again.