My cats are real pistols to get into the carrier. In fact, one day I had to cancel a vet appointment because I just couldn't get them in there. I find the best room for the "capture" is the bathroom because there's nowhere for them to hide. Even so, I now make all of my kitty appointments at night because it takes both hubby and me to get them in the carrier.

Regarding sedation, I know Christiansmommy had to use it on Gabe for his routine vet visits. I don't know the name of the medicine but perhaps she will chime in here or Sallyanne may see this. I don't remember any bad side effects.

I have actually trimmed Trevor's nails while he was sleeping. He is a heavy sleeper and is used to me carressing him during his naps. I can't get them all done before he wakes up, but hey there is always another nap just around the corner.