despite the sadness involving this.. it got me curious as to what may have caused it... I came across this on a site...
" I have read that in a few cases a bitch can have an improper hormone balance at, and following, the time of whelp which can cause her to not be in a "mothering" mode; to the end that she sees the puppies as "invaders" and will either abandon or harm them. The articles indicated that this was usually a first litter issue with a bitch affected thus, and that the production of any future litters had to be supervised. This supervision involved the testing of the bitch's blood to verify that the various hormones were at their proper level at, and following, the time of whelp, and if they were not some supplementation was done to correct the hormone level.
And of course I think there is the very rare case where the bitch is mentally deficient and can never be a proper mother to her puppies, but of course I can't quantify that."
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