I am currently using Hill's Science Diet. Pinot eats the Indoor Cat (dry) in the morning and I mix a little of the moist Science Diet that comes in a pouch for her dinner. She eats every crumb and has no trouble. We had previously raised cats on Purina with no issues (in the days when there wasn't as much choice!), but when we got Pinot from the SPCA the Science Diet was given to us, and she had bad health issues, so we stuck with it because it was what she knew. She is healthy now and has a very good appetite!