I just reread some of this thread that I had missed.

1st, after the first injection, YOU should be able to give them at home. Make them show you how (it is a sub-Q shot)

2nd, the dosage WILL decrease once it is shown that RBCs are being made again.

3rd, The Epogen I got was from a human compounding pharmacy, not through the vet. Possibly the price might be different at a local pharmacy.

Best of luck with this. I hope it can perk her up fast.