Every heat cycle a female goes through increases the chance of her getting cancer when she is older. Having your female spayed before she goes through her first heat cycle is a big health benefit. A female who is never spayed is about guaranteed to get cancer.
Breeding adds a lot of health concerns. I personally would never want my dog to go through any of that. Small dogs (more often than large) have hard time birthing their pups, usually resulting in an expensive (and often risky) c-section. They can even die giving birth.
Breeding responsibly is very expensive, and if you're not breeding responsibly you shouldn't be breeding at all. Breeding needs to be taken seriously, it should not be done by just anyone who has an un-spayed or un-neutered dog. A lot needs to go into it to ensure the health and safety of both the male & female parent dogs and the puppies too.
A lot of people here know a lot more about it than I do. There is a lot involved and I don't know all of what goes into it.
This site provides a lot of information and links to information about the ups and downs of breeding.
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