You have my sincerest sympathy. I haven't had a migrane in a while (knock on wood) but would be out of commission for days. It'll probably take a few days or weeks for your body to adjust. At least that's what happened to me when I was taking Nuerontin and 6 other pills for my spine before my surgeries. It sounds like they come on at a timely basis since you expect one this weekend. Maybe it's a hormonal thing as well? At least you're seing a nuerologist. My friend's daughter suffered all her life until she finally saw one. He took one look at her (she was in college) and saw that she already had mini strokes because her mouth was crooked and one side of her face sagged. I'm just saying that because migraines are nasty and awful and dangerous. I pray the meds help you. Nobody deserves to suffer like that. I hope you can enjoy the holidays. {HUGS}