I just went back for my 6 month check up with my nuerologist and she gave me Topomax to take at bedtime. Started with one a night for a week and then two a night now and this month I didn't get a migraine after my cycle, even with the stress of the death in the family. If the imitrex doesn't work, ask for Maxalt. I had taken the imitrex at first and it didn't touch the migraine and the maxalt really works.