Bottle feeding is time consuming, but worth it. The kitten must be kept warm as it can't regulate body temperature for several weeks. A heating pad set on low, and well covered to prevent the kitten from getting burned works well. Never feed a kitten on it's back as a human infant would be fed. Lay the kitten on it's belly to nurse. Milk can very easily aspirate into lungs otherwise. KMR is a complete substitute for a cats milk, and as Catnapper said, every few hours around the clock! You'll have to be prepared to get up several times during the night to keep the baby alive. You may want to try removing your nursing cats own kittens, feed the mom cat something really stinky like sardines, and rub some of the sardine juice all over the newborn kitten. I've introduced many orphans to a surrogate mom cat this way. If you end up needing to bottle feed in the end, I use very sharp scissors and cut a small X going from the tip of the nipple down. Peircing the tip with a needle never worked for me. Another thing you may want to try, is contacting area shelters in the chance there is a cat with newborns in a foster home. This will save you a lot of lost sleep. Good luck, and keep us posted!