Debbie, you might be right about her post-spay experiences stressing her out and having something to do with the increase in antisocial behavior. Of course, I only have two cats and two years worth of experience, so I don’t know much. But, after we had Rizzo spayed, he went through a panicky, antisocial phase where he did NOT trust us. And, you have to understand how weird that was. Rizzo is a MUSH. He loves people. But for a few weeks or a month or so there, every time we picked him up, he would kick and flail and scratch until he got down. And then he would puff up his tail and howl/growl at us and slink around with huge eyes for hours. If we tried to pet him, he’d run away. He didn’t seem to be in pain, just good and scared. It was So. Weird. I was about at my wits’ end. I felt so rejected and guilty and…I dunno, just bad. But, on my husband’s advice, I kept picking him up anyway (and so did hubby), and we treated him just like always, and eventually (a month or two) he was back to being his usual, lovey, gentle, goofy self. Nowadays he actually lets us put him on our laps upside down like a baby, and he’ll just lie there looking at us like, “What? Is this necessary? Dude, you’re *mussing* me,” until we let him go.

Sounds like Lizzie has a wild (calico. Heh) streak in her anyway, but this current phase of total don’t-touch-me-ishness might pass once she realizes that no one’s going to cart her off to the white coats anytime soon!