Yes, Oreo has this problem. Her vet called it "spay incontinence" after she ruled out a UTI and other possibilities. This leaking while sleeping in houstrained, young, spayed dogs can be due to an estrogen depletion. There are two meds that do help, and which you take depends on which drug the individual dog tolerates better, your vet, and the availability in your area.
The first is PPA, or phenylpropanolamine; it was the active ingredient in some diet pills for humans that have been banned, but it seems to be safe for dogs. Oreo took this once a day and had good results with stopping the leaking, but a side effect for her was restlessness.
The second is DES, or diethylstilbestrol; this is a synthetic estrogen also banned from human use but OK for dogs in low doses. Oreo now takes this one pill twice a week also with good results. I've read a side effect with high doses may be bone marrow depletion, but our vet says that at our dose she is OK.
There is more information on both if you search Google with the drug name and "dogs".
We have to buy both drugs from a compounding pharmacy at the local (human) hospital, but they don't cost too much.
Sorry this is long, but I hope this helps! Others here on PT also have this problem, so you should get lots of info. Best wishes to the pup!
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