I have yet to need to sedate any of my cats, so I have no experience in that field.
But I can suggest to try making the carrier "cat friendly". Since I FEED my cats in carriers, they do not fear them. You can achieve this by leaving a carrier out at all times, lining it with something comfortable to lay on, and put treats in it, way in the back so they need to go in.
Also, you could use a pillow case to put over Cirrus and they tie it and put it in the carrier. This is safe, as my vet actually recommends this.
Cirrus may also calm down with time and experience.
Better luck to you Wed.