Thank you all for your kind, caring, responses. KAK, I only had him off Wellness for about 2 days. He is used to eating a variety of wet food. I feed him Royal Canin (he loves this food!) Wellness, Nutro Natural Choice, and Merrick Before Grain. Ming is picky, he's a cat after all, and eats these choices some days and other days NONE of them are worthy of a taste. So, I keep his dry very consistent. He eats either Blue Wilderness Duck or Solid Gold Indigo Moon. He loves both of these and has been on them for some time. My guess is he just got some sort of stomach bug because he never really stopped eating or drinkng, he just got lethargic and isolated himself. With his history, this is enough for a vet visit. I am so happy my big boy is fine now. He weighs in at a hefty 21lbs, 10 oz. THAT"S a big cat! His teeth are fine, his heart is fine, so I guess he was just under the weather for a couple of days. Again, thank you everyone for caring about my sweet Siamese boy.