Do you have carpets? Hardwood or other smooth flooring is better, traps less dander. Do you have a vacuum with a HEPA filter?

When I am at my sister-in-law's house, we move a hard wooden chair into the living room so I can sit with everyone and chat, and still breathe. Otherwise, it doesn't matter how much she vacuums - and she is a meticulous housekeeper - if I sit on one of the upholstered chairs or couches, I am miserable and snuffly. Wooden chair - fine! Not only do her kitties not bother with hard chairs when comfy surfaces are around, but when you wipe one off, the dander is gone - nothing for it to sink into.

Just my two cents!