I use desitin cream with every single diaper change... I slather it on and haven't had a problem with diaper rash yet... knock on wood. I really like Desitin.

But if the Dr gave you a prescription for her and it's not working I think you should go back and let the Dr know and see if maybe she needs something else...

I agree with letting her go diaper free for short periods during the day and make sure her bum is dry before applying any cream... change frequently and use Desitin with every change... and don't worry... you can't put too much on in my experience lol hubby makes fun of me cause I slather it on where he uses half what I do and rubs it in.... But so far so good.

I hope you can get it cleared up soon. it sucks for both of you.