It would definitely depend on the circumstances - and the pet. Since human offspring will never be a concern for me, I am able to give my all to the animals I share my life with, and that has included a large chunk of my money at times. Heck, I had rats, that should say a lot! However, I could not afford $45,000, and I don't know what I would do under those circumstances. If I had the resources, and the odds of a good quality of life were good after the procedure, I would do it.