My uncle's partner did almost the same thing last summer.

They had us and a guest at their house for dinner. Kyle lost his legs at age 16 from a skiing accident (he is now in his late 40's) . We were all eating dinner and it came out that Kyle saved all his toothbrushes. No particular reason why, but he keeps them all on the counter in the bathroom, he says he likes looking at all the pretty colors. George then joking asked "Do you also save your toenails??!!" Instantly George realized what he had just said, and became a deep purplish-red. Without missing a beat, Kyle looked up at him and said "Yes, I probably would, if I still had them!". There was a (long) moment of silence then we all burst out laughing. George was SO embarrased, but Kyle managed to ease him of the pain.