I have a dog who has been on Rimadyl for more than two years now. We have his liver enzymes checked three times a year. If there were ever any indication that the medication might be affecting his liver we would have them checked more frequently. So far, no problems.
He's had problems with limping since we adopted him, due to an injury of unknown origin that healed poorly and went arthritic before he was part of our family. The Rimadyl helps tremendously. He only limps now if he exercises excessively. (Meaning regular walks are fine, but the day I took him on a five-mile hike he was sore afterwards)
For unknown reasons, Labs seem to be the most susceptible to liver problems from Rimadyl, but I have seen in successfully used in labs, as long as the doctor and the owner are both aware of the risk and are cautious when starting the pet on rimadyl.






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RIP Sabrina June 16 2011
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