Quote Originally Posted by dragondawg
Why would you want to give heartworm pills daily? Also since you are a Collie fan, you have to worry about anything with Ivermectin in it, and that includes Dimmitrol.

Dimmitrol is not suitable for all breeds e.g. Collie breeds, Collie crosses and some Shepherd breeds. For Ivermectin sensitive breeds, we recommend
Sentinel Spectrum, Interceptor Spectrum, Proheart or Guardian.

Dimmitrol reference

The problem that Collies have is a genetic trait that allows more of the Ivermectin to pass through the blood/brain barrier via a cellular pump. It creates higher than usual Ivermectin concentrations in the brain leading to possible neurological problems (e.g. seizures or worse). Collies also have the same problem when dealing with Immonium A/D. It's not universal for Collies but does have a very high incidence due to the genetic mutation.

I have my N Carolina puppies on Sentinel year round, which also hits a variety of other worms. Once a month seems cheap enough.
Yes.. I am well aware of the ivermectin sensitivity in Collies.. as well as immodium and a whole list of other possible problem drugs in Collies and Collie like breeds... Daily dimmitrol does not have ivermectin in it.. the dimmitrol labled for once a month use does, which is what the link you posted was for.. once a month dimmitrol. Daily dimmitrol is safe, though I will agree that doing heartworm pills once a day would be a pain in the butt!..

Actually I know several breeders who use daily dimmitrol or other types of daily heartworm prevention with their Collies. I have had Collies for 13yrs, and have used interceptor (and on occasion sentinel) the whole time.. I am just trying to get other peoples opinions on the daily heartworm prevention.

Also there is a DNA test you can run on your dogs to see if they carry the mutant gene (MDR1) for ivermectin sensitivity... which on down the road I plan to run one a couple of my dogs. Even though, if you read the info about the MDR1 test and the studies done on ivermectin sesitivity.. it shows that for most collies (with the mutant gene of course), the dosage of ivermectin in hartguard did not affect them... they didn't show any side affects until several times the normal dose was given.. but they could handle a much lower "over dose" of ivermectin than other breeds... however Collies were ALSO shown to react to a much lower dose of milbemycin (interceptor) than other breeds as well..... just kind of an FYI. I'm really not a clueless collie owner, which apparently it sounded like from my first post..