Don't know if this will help.

I had one Anatolian girl that had a brief case of pyoderma in one toe on one foot. We went to our vet who is both a large and small animal practitioner. The treatment we used for her included 10 day of antibiotics (I think it was Keflex, been a long time) and we also used Epsom salt soaks on her foot to help 'draw out' the infection in her foot. (cellular reaction to hypertonic solution). Her case was not severe or chronic, she had only one oversized fat and tender toe. It cleared up very quickly before the week was done. I used gallon sized ziplock bag to hold her soak around her foot. Made her sit by me while I did other work.

People drove from miles around with their stock trailers just to have this vet look at a calf or horse, while his lobby was often full of small pets (cats and dogs). Cool vet, retired now.

Anyway, the use of epsom salts with large animal cases of pyoderma is very common, but for some reason, small pets doctors (unless they are large animal practitioners too) don't usually offer epsom salts as part of the solution.

Example: A friend of mine in Australia had an aged Anatolian Shepherd male that developed a case of pyoderma. The vet she originally saw was a 'pet vet' in town, who gave all kinds of 'modern day' treatments to heal her dog including prednisone which can actually increase immune compromise. The problem got worse over two weeks (no improvement) and the dog lost one toenail before the gal gave up and went to her horse vet.

The horse vet suggested using epsom salt soaks. The dog had no puss within the first week and was back to normal before the second week was over.

Your mileage will probably differ. Both of these working dogs were not prone to allergy and other immune compromise. The Australian dog was on a raw diet, mine got raw once a week at least. They were primarily outdoor dogs who had healthy exposure to dirt and livestock (sheep, chicken and horse). I didn't see epsom salts mentioned so I thought I would.

Good luck!