I have found that Cortaid cream works wonders. It takes the itch away which, to me, is the main problem. I never found Calomine lotion to do a thing except look bad. I know it probably helps dry the pustules but I never had much luck with it. Maybe the new kind that Karen mentioned is improved. The worst thing to me is getting into the shower and having the water hit the itchy patch. It makes you want to start scratching but I suppress that until I am able to get out and grab the Cortaid.