I am so very sorry to hear about this problem and will keep you and Ms Sophie in my prayers!!! I hate it when I feel helpless so I understand.

Something to keep in mind, is that if the news is bad or you don't like what you hear, DO find another rabbit-specialist vet and get a 2nd or even 3rd opinion. While rabbit-specialist vets are rarer than hens teeth, I have found that they do not always agree on diagnosis and/or treatments.

Why? Some vets continue to stay on top of bunny health issues and go to bunny health conferences while others end their education at graduation. A consideration would be to take Sophie to a well-known vet school in your state.... for example here in Mich. Michigan State University has an excellent vet program and the instructors know all of the latest treatments and procedures. We have found it worth the time, money and effort.

I'm wondering if maybe Sophie has a abcess. They can sometimes be removed or drained and in other instances it's better to do nothing...depends on the site. We have several buns at the sanctuary that have been living with those things for years and they are otherwise healthy.

I do wish you the best of good luck. Casey sez "HEY!" to Ms. Sophie and sends her a nose twitch and her vey best thoughts.