I was on anti depressents in the late '80's, the 'other" kind before ssri's. then in the '90's I was diagnosed with bi-polar and have made the rounds with ssri and anti convulsant type combos. I've finally ended up with prozac & topamax both which have the bonus of helping me with migrains which were almost a daily occurance. Different types of med effect people differentlly, and some people do react to them with anger - small percentage, but biollogically there are other things going on as well. prozac all take about 6 weeks to get into the system and see/feel difference and the same to exit. Also while these meds are ok alone, it is best to seek/have therepy during treatment to understand what your're going through, and 'talk' it out.

I had my share of going on & off the meds due to the side effects. For me that really is not an option. I do well on them, and I do have seasonal dosage changes, so that may be something to consider, sometimes you may need more sometimes less.