In your place, I would take Cosmo to one of the cat specialists for one assessment and conference with a true expert very soon. Ask your vet for Cosmo's record, especially his blood results, and tell him what you are doing. He should understand. I've done it with several of my cats for different things and my vet was completely understanding. Actually, the fact that you are seeking more expert opinion may jolt your vet out of his seeming lethargy. This visit will make you feel that you are doing everything you can for Cosmo, and will give you both reassurance and confidence to continue with his treatment. It's a very positive step which I know always makes me feel better.

Another poster mentioned kidney transplant and I remember wanting to do this very badly for both my Artful Dodger and Ted, but there was no way that I could afford it. I would have taken them to U.C. Davis, which is the closest veterinary transplant center to Seattle. There, they use cats from humane societies as donors, and the kidney recipient's guardian has to take the donor cat home with them, and take care of them for life. My vet told me that they do not remove the malfunctioning kidney from the cat but put the donor kidney in the chest cavity - that surprised me.