I personally have not had an adrenal ferret, yet, knock on wood. But do of many many people that do/did.
I know a lot that had surgery & a lot that medicated. Medication (lupron) does not cure like the surgery but many have success with it.

Most people I know just get the surgery done as it is healthier for them and cheaper in the long run. They only give the lupron if the ferret is not a good candidate for surgery (ie. very old, sick, malnurished etc..)