Jonah has sensitive skin, and struggled with both rash and yeast infections alot.

I did not find desitin or powder to be an effective barrier against moisture. I used aquafor, and made sure I super dried his bottom, allowing him to go without diaper when feasible, and slather on a huge ton of aquafor.

Frequent diaper changes are an absolute must. Yeast infections need antibiotics, and if you are BF, make sure you are treated as well.

In place of aquafor, you can use vasoline, but, aquafor is much easier to apply, IMO.