Welcome to PT!
Sorry to hear about your troubles.
This sure is a toughie.
I imagine you have tried just about everything w/ your vet but maybe seek a second opinion?
Have you consulted w/ a behavorist?


I personally don't think a dog sitter would work too awful much if they can just stay for a little while.
BUT if you can set up a camera in your home & see if there is a certain time of day she usually starts to be destructive, or if she waits until a certain amount of time has passed after you left before she starts to be destructive, and see if she is destructive all day.

If she only acts up once in a while at certain times, you may have the dog sitter come at those times & that may help.


Also the nothing in life is free training method may help, that is where the dog has to obey a command before she gets ANYTHING, she has to sit before she gets fed, lay down before she gets petted, shake before you let her outside etc...

And make sure she gets plenty of exercise (a tired dog is a good dog)
If you can have a play session (or walk or exercise etc..) at the same time every day it may help. Actually having her on a set schedule for everything may help some.

Good luck