I have a really small purse, but it's packed well:

Matching wallet
Matching checkbook
Lipstick
Keys
3 dog bones (all different kinds )
Cell phone
Cover Girl pressed powder compact
Advil
Pill pack for daily pill taking
Hair pick
Orbit White peppermint flavored gum (yummy)
Cool knife thingy that has a screwdriver, scissor, knife, nail file
Prescription eye drops
Gum
Extra cell phone battery
Purell hand sanitizer
Gold Bond Ultimate lotion