I have a mixed household. Even though Eddie has his claws, is younger, and half again as big, Edwina swats him all the time. Of course it doesn't really faze Eddie. I have never seen him swat her back.

We trim their nails regularly using the "guillotine" type of nail scissors. We take the "two on one" approach. I hold the cat and the leg to which the claw is attached while my husband wields the scissors.