Pill pockets work wonders with the nasty-tasting pills.

And Mowgli will eat about anything mixed with food, so if I've got to pill him, I get him a bowl with a few pieces of food, a couple of treats, and the pills and in about two minutes the bowl is licked clean.

Zelda, on the other hand, is smarter and will eat everything but the medicine, which means I have to take a more hands on approach. I get on the floor and trap her between my knees so that my hands are free. With my left hand, I grab behind her head, fingers going around her upper jaws and gently pull her head so she's looking up. Then, holding the pill in my right hand, I ease her lower jaw open, drop that pill in as far back as it'll go, and then hold her mouth closed and rub her throat until she finally swallows. And boy will she ever sit there with that pill balancing on the back of her tongue for a LONG while!

With liquid medicine, I would probably have to use the Zelda method on both cats. Never had to try liquids with Mowg before. But anyway, I haven't gotten clawed or bitten yet while giving meds yet, though, it is something I do worry about a bit when I've got my fingers that close to the teeth. But you've gotta do what you've gotta do!