I usually only spending around $50 (per cat) for my annual. Normally the visit to the vet costs $35 but for annual visits they drop the charge (I think it's just to get more people in there for vaccinations) Each shot runs around $10 - $13 and are adminstered by a tech. For an additional $10 the vet will come in and check your kitty to make sure that everything looks good. I always spend the additional $10 for the vet to give my kitties a look over, but I know that a lot of people don't.