The other medical option, aside from Proin is DES, or diethylstilbesterol, a hormone. It's a little more "risky" than Proin, requiring regular blood chemistry monitoring, but quite effective. My Cody has been on Proin 50 for years and until recently, it was working great. After months of frequent episodes of leaking large amts., as you say, waking up to a totally soaked side/backside, she was started on DES, at a reduced dosage. They start the dog off on a loading dose, then reduce it to 1 pill twice weekly. Luckily, 1 dose weekly in combo. with the Proin, has done the trick At that dosage, there is minimal chance of bone marrow depression, though we still do blood work every 3 months.

I'm not familiar with urinary/reproductive tract warts in doggies, but they are common in women and the only cure is surgical removal. Often cryosurgery, or removing them with "cold," is an easy and effective mode of removal. I'd talk about some other options further with your vet They can get nasty and infected if not removed, especially considering the area.

Hope this helps a bit...hugs to your pupper! And please check back with us and tell us how she's doing