We are treating our 14 year old female Lab with a hormone that the vet provided for us. She takes one capsule, every 3 days. I am not sure that it is as effective now as it was when we first started though. I bought a waterproof bed for Murphy and just wash the cover when she has an accident on it. Unfortunately, because we have so much carpet in our homes, I have had to block her in two rooms, but she has our other 3 dogs to keep her company.

Good luck.