I have had to give both liquid and pills. The easiest way I have found for both is to sit on my knees with my ankles crossed and the kitty between my knees. I then force open their mouth and either squeeze the liquid in with an eye dropper or drop the pill half down their throat. They can't back up to get away and I don't get scratched either. Works pretty well for me. Although I usually have to chase them down to start with.