If it is a liquid what I did when Cubby was on liquid medication. I mixed it in with some kitten milk. Of course I call the vet first to make sure it was ok. I always gave him a little extra so he would get the full amout. That worked best for all of us. I couldn't hold him down at all. As small as cats are you would think we would be able to hold them down but I have been very unsuccessful in that. If it's a pill I always wrap my arm around him and grab his face and open his mouth at the same time and pop the pill in as far as I can. Then if he spits it up I re do it all over again until I get it down him.

Katie

P.S.
I hope that helps. Good luck I think you might need it.