Yes, I have scruffed Abner at times. I do the same thing that Jen described. You MUST support a grown cats weight otherwise you will end up hurting them.

Abner is my Alpha cat and likes to show all my other cats that he is # 1, so at times he needs a good scruffing to calm him down a bit. Also with my RB Tobias, he needed to be scruffed at the vets, he was the hardest cat I have had in my entire life to have to give a shot or medicine to. Scruffing him let me have a little more control over him.