I have a female corgi with arthritis and we use glucosamine with MSM, powder form of Ester-C and evening of primrose oil capsules and we have had great results. She used to yelp when she would wake up in the morning and after a month of the vitamin use (she has been using this formula for about 2 or 3 years) she runs around and plays. She can over do it but for the most part she is in much better health than I ever thought possible. Good luck!