Jazz had the same reaction the first time she saw a young child. She had been around older children a few times (11 yrs and up) and was okay with them. The first time she saw my husband's 5 year old nephew she almost had heart failure trying to get out of the room. When I finally coaxed her back she would let everyone pet her but the 5 year old.

Ripley has always disliked children too - he would go as far as growl and hiss at them.

As far as her reaction to the house I bet the larger size is probably the problem.