All of our female dogs have been spayed. All had no problems. One girl (Black lab - greyhound) became incontient at night at age 13 and the vet said it does sometimes occur with spayed dogs when they get on in age (just like some humans - the muscles are not as tight) he put her on a hormone pill I think it was 3x a week after the 1st dose the problem was soloved. I wish humans could heal as fast as some dogs do.