you may be bigger than the cat, but I think he wins on the sharp claws dept! I KNOW exactly how you feel, I am like you... I was very upset and desparate when my cats, 4 of them needing 2 meds , each med 4 X a day! it was hell! I guess what the others say, if you really hunt him down and force him then maybe he would get used to it... who knows. what does your vet say? he just really might need kitty prozac or something like it. have you tried the feliway? and a drink for yourself after each "medicating the cat" experience! let it go for a day or 2, he will be ok for just 2 days, it will calm him somewhat. then try tuna, peoples tuna, sardines, anything! baby and spoil him, while you get the feliway...?feliway might not work, but I think it will calm him, and if not then ask your vet about behavior modification because if this is a med he needs for his lifetime, he has to have it.