I did talk to my vet and he said that I could give Jack 2 pills a day at 1000 mg each. The bottle I have will last about 3 months and the vet said that by then I should know if it's working or not. I feel like I'm drugging up my dog all the time, but hopefully this will help him in some way. It breaks my heart sometimes when he tries to get up from laying down and it seems like his back legs aren't going to hold him. So I guess we will see what happens!