Carina has been taken Glucosamin/MSM for the last two weeks. I took her to the vet because she looked like she had trouble going up steps and getting up. She has arthritis in her back legs, which is not unusual for a 10 years old pup. Since I didn't want to fool around with things I didn't know, I got the powder form that my vet recommended ($60.00 for six months supply) and I give her two scoops every day with her food. It will take from four to five weeks to really show results but I heard very good reports about it.