What suburb are you going to? You might be able to take the commuter train into the city and take a cab from there. If you do drive, one thing to note is that Upper and Lower Wacker Drive have just been closed for 2 years as they are starting repair work and these streets. The Shedd Aquarium and Museum of Science and Industry are also wonderful places to visit. This weekend the IKC is having a big dog show at McCormick Place. Too bad your visit won't coincide with that.