Bastet would meow the leg off a table if I don't let her in my room. She chooses whether she sleeps on th bed or not but she makes a rucuss if she isn't with me.

Despite cats being independent they sure rely on us for company a great deal!

I would keep the door ajar for starters.
Feed them both just before you go to bed so they get out of that habit of begging for food at 4am in the morning.
If that doesn't stop then its bathroom kitty timeout time.

Worked for me!