Thank you for your replies. Misser was taken to the vet that the woman who is keeping the yard, used for her own cats. She managed the car ride well, and I was told she went peacefully. However, she bit the woman who had signed up to care for her. In the process, she lost a tooth, so they must have been pretty bad.

A black kitty have been coming over to our yard in the evenings in recent years, he seemed to get along well with Misser and we believe he is the father of her black kittens. He will surely miss her, but perhaps take over her domain.

Rest in peace, Misser and meet the other kitties who went before you.