Any time a kitty has a lump, it's of great concern. Take her as soon as you can. Use a calming collar, or Feliway, to relax her some. Leave the carrier out ahead of time, door open with her favorite blanket.
Before anesthesia, the vet might consider a fine needle aspirate (awake, usually painless) to determine if there's malignancy. Also, the vet will know how to handle her heart issue, in case anesthesia is needed.
If at all possible, calm yourself down as well. Kitties always know when their parents are upset.
Good luck and keep us updated.
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